Table 4.

Average log-odd ratios for two binding sites to be co-localized

	Homodimer	Heterodimer	Peptide	S.Peptide	DNA	RNA	Ligand	Solvent
Homodimer	0.12	0.13	−0.35	−0.30	−0.02	−0.60	−0.09	0.02
Heterodimer	0.13		0.79	0.63	0.09	−0.85	0.12	−0.06
Peptide	−0.35	0.79	−0.02	0.84			−0.09	−0.23
S.Peptide	−0.30	0.63	0.84				0.30	−0.15
DNA	−0.02	0.09			0.34		0.63	−0.12
RNA	−0.60	−0.85				2.37	0.43	0.04
Ligand	−0.09	0.12	−0.09	0.30	0.63	0.43	−1.56	0.15
Solvent	0.02	−0.06	−0.23	−0.15	−0.12	0.04	0.15	−0.01

Each cell corresponds to the log-odd ratio of the observed probability of having a binding site type A overlapping a binding site type B over the expected probability of having A and B overlapping. Positive values indicate favorable overlapping/polyvalence between the binding site types A and B, whereas negative values indicate unfavorable overlapping/polyvalence. Empty cells are unsolved values due to an insufficient number of overlaps between the two considered binding sites; however, they should indicate low log-odd values.