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. 2010 Sep 13;39(1):104–118. doi: 10.1093/nar/gkq774

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© The Author(s) 2010. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — DNA methylation changes of DNA repetitive elements induced by DNMT isoforms. (A) DNA methylation changes of two interspersed DNA repeats, LINE1 and AluYb8. (B) DNA methylation changes of two tandem repeats, Sat-α and NBL-2. DNA methylation in HEK 293T cells treated with 5-aza-2′-deoxycytidine, a DNA methylation inhibitor (decreased methylation control), or M.SssI, a CpG methyltransferase (fully methylated control), is shown as 293T/DAC or 293T/M.SssI, respectively. Two independent transfection experiments are indicated as cell line 1 and cell line 2.