Table I.
Differentially expressed proteins selected by the TFold Analysis. All proteins were found to be statistically differentially expressed (p < 0.01) and have an absolute fold change greater than 2.5. The set of proteins also satisfies the BH-FDR of 0.05 criterion. A positive fold indicates a greater expression on the A172r.
| IPI | Fold Change | Description |
|---|---|---|
| IPI00027493.1 | 5.36 | SLC3A2;LOC442497 4F2 cell-surface antigen heavy chain |
| IPI00382470.3 | 4.69 | HSP90AA1 Heat shock protein HSP 90-alpha 2 |
| IPI00013744.1 | 4.47 | ITGA2 Integrin alpha-2 precursor |
| IPI00384280.5 | 3.98 | PCYOX1 Prenylcysteine oxidase precursor |
| IPI00334775.6 | 3.72 | HSP90AB1 85 kDa protein |
| IPI00033494.3 | 3.71 | MRLC2 Myosin regulatory light chain |
| IPI00298237.7 | 3.67 | TPP1 Isoform 1 of Tripeptidyl-peptidase 1 precursor |
| IPI00332106.2 | 3.56 | PBXIP1 Pre-B-cell leukemia transcription factor-interacting protein 1 |
| IPI00065486.2 | 3.55 | ABCB6 Isoform 4 of Mitochondrial ATP-binding cassette subfamily B member 6 |
| IPI00031357.1 | 3.43 | PPOX Protoporphyrinogen oxidase |
| IPI00304925.5 | 3.13 | HSPA1B;HSPA1A Heat shock 70 kDa protein 1 |
| IPI00029133.4 | 2.90 | ATP5F1 ATP synthase B chain, mitochondrial precursor |
| IPI00099463.2 | 2.86 | SGPL1 Sphingosine-1-phosphate lyase 1 |
| IPI00003527.5 | -2.50 | SLC9A3R1 Ezrin-radixin-moesin-binding phosphoprotein 50 |
| IPI00456940.5 | -2.50 | RPL7L1 Ribosomal protein L7-like 1 |
| IPI00106847.3 | -2.50 | MSH6 Isoform GTBP-alt of DNA mismatch repair protein MSH6 |
| IPI00186290.6 | -2.51 | EEF2 Elongation factor 2 |
| IPI00000816.1 | -2.52 | YWHAE 14-3-3 protein epsilon |
| IPI00012773.1 | -2.57 | MTA1 Isoform Long of Metastasis-associated protein MTA1 |
| IPI00029111.2 | -2.58 | DPYSL3 DPYSL3 protein |
| IPI00007207.2 | -2.60 | LIPA Isoform 1 of Lysosomal acid lipase/cholesteryl ester hydrolase precursor |
| IPI00005107.2 | -2.64 | NPC1 Niemann-Pick C1 protein precursor |
| IPI00029019.5 | -2.75 | UBAP2L Isoform 2 of Ubiquitin-associated protein 2-like |
| IPI00169383.3 | -2.77 | PGK1 Phosphoglycerate kinase 1 |
| IPI00183786.1 | -2.89 | FADS2 fatty acid desaturase 2 |
| IPI00008868.3 | -2.97 | MAP1B Microtubule-associated protein 1B |
| IPI00218918.5 | -3.00 | ANXA1 Annexin A1 |
| IPI00000875.6 | -3.07 | EEF1G Elongation factor 1-gamma |
| IPI00376798.3 | -3.10 | RPL11 Isoform 1 of 60S ribosomal protein L11 |
| IPI00221093.7 | -3.13 | RPS17 40S ribosomal protein S17 |
| IPI00020567.1 | -3.25 | ARHGAP1 Rho GTPase-activating protein 1 |
| IPI00299086.3 | -3.33 | SDCBP Syntenin-1 |
| IPI00479018.2 | -3.33 | SDCBP Syntenin isoform 3 |
| IPI00297261.3 | -3.50 | PTPN1 Tyrosine-protein phosphatase non-receptor type 1 |
| IPI00000070.1 | -3.53 | LDLR Low-density lipoprotein receptor precursor |
| IPI00739099.2 | -3.64 | COL5A2 Collagen alpha-2(V) chain precursor |
| IPI00418471.6 | -3.80 | VIM Vimentin |
| IPI00296141.3 | -3.82 | DPP7 Dipeptidyl-peptidase 2 precursor |
| IPI00008894.2 | -3.92 | CPA4 Carboxypeptidase A4 precursor |
| IPI00479186.5 | -3.98 | PKM2 Isoform M2 of Pyruvate kinase isozymes M1/M2 |
| IPI00013068.1 | -4.00 | EIF3S6 Eukaryotic translation initiation factor 3 subunit 6 |
| IPI00072377.1 | -4.24 | SET Isoform 1 of Protein SET |
| IPI00289758.6 | -4.25 | CAPN2 Calpain-2 catalytic subunit precursor |
| IPI00025491.1 | -4.27 | EIF4A1 Eukaryotic initiation factor 4A-I |
| IPI00328298.6 | -4.29 | SMC4 Isoform 2 of Structural maintenance of chromosomes protein 4 |
| IPI00007812.1 | -4.56 | ATP6V1B2 Vacuolar ATP synthase subunit B, brain isoform |
| IPI00043598.2 | -4.63 | IKIP CDNA FLJ31051 fis, clone HSYRA2000605, weakly similar to MYOSIN HEAVY CHAIN, CLONE 203 |
| IPI00027422.1 | -4.69 | ITGB4 Isoform Beta-4C of Integrin beta-4 precursor |
| IPI00396171.3 | -4.88 | MAP4 Isoform 1 of Microtubule-associated protein 4 |
| IPI00184330.5 | -5.78 | MCM2 DNA replication licensing factor MCM2 |
| IPI00465248.5 | -6.05 | ENO1 Isoform alpha-enolase of Alpha-enolase |
| IPI00021033.2 | -6.71 | COL3A1 Isoform 1 of Collagen alpha-1(III) chain precursor |
| IPI00027626.3 | -6.90 | CCT6A T-complex protein 1 subunit zeta |
| IPI00784347.2 | -8.92 | KRT18 Keratin, type I cytoskeletal 18 |
| IPI00026781.2 | -10.00 | FASN Fatty acid synthase |
| IPI00554648.3 | -11.31 | KRT8 Keratin, type II cytoskeletal 8 |
| IPI00012011.6 | -15.64 | CFL1 Cofilin-1 |