Table 4.
% Variance in Probability of Onset in 5 Years Explained After Controlling for UHDRS Motor Score
| Task – Conceptually distinct task component | % Variance Explained Above UHDRS Motor Score (Adj R-sq = 0.29) |
|---|---|
| Benton Facial Recognition Test: Total correct | 0.8 |
| Category Learning Tasks | (0.8) |
| Rule-based: % blocks completed | 0.8 |
| Non-verbalizable: Max % correct in a block | 0.6 |
| Emotion Tasks | (5.5)b |
| Emotion Recognition: # correct (negative) | 1.3a |
| Dynamic Emotion Recognition: # correct (negative) | 5.4b |
| HVLT-R – Total learning (Trials 1–3) | 2.9b |
| N-Back Tasks | (2.0)a |
| 1-back discriminability: Foils | 1.0 |
| 2-back discriminability: Foils | 1.3a |
| Phonemic Verbal Fluency: Total correct | 0.4 |
| Cued Movement Sequence Task | (8.8)b |
| Low cue level: SD | 5.1b |
| Medium cue level: SD | 8.3b |
| High cue level: SD | 1.7a |
| Serial Response Time Task – Learning effect (B5-B4) | 0.3 |
| Simple and 2-Choice Response Time Task | (2.9)b |
| Simple Response Time: Mean | 0.9 |
| 2-choice Response Time: Mean | 2.7b |
| Stroop | (3.8)b |
| Stroop Color: Total correct | 3.4b |
| Stroop Word: Total correct | 1.9a |
| Stroop Interference: Total correct | 2.6b |
| Symbol Digit Modalities Test: Total correct | 4.3b |
| Tapping | (14.5)b |
| Speeded Tapping Nondominant Finger: Mean of ITIs | 9.7b |
| Self Timed Tapping Alternating Thumbs: SD of ITIs | 9.1b |
| Tower Tasks | (0.6) |
| Tower 3: Mean # moves (4 trials) | 0.6 |
| Tower 4: Mean # moves (4 trials) | 0.2 |
| Trail Making Tests | (3.4)b |
| Trails A: Seconds to completion | 3.1b |
| Trails B: Seconds to completion | 1.4a |
| UPSIT: Total correct | 7.4b |
| WAIS-III Letter-Number | 0.2 |
| WASI – Matrix: Raw score | 0.2 |
| WASI – Vocab: Raw score | 1.0 |
Note.
a
indicates p < 0.05;
b
indicates p < 0.01; Parentheses are used for linear regressions that involved multiple variables typically considered in conjunction with each other (e.g. Trials A and B), or a set of variables assessing highly related functions (e.g, Speeded and Self-Timed Tapping). SD = standard deviation; HVLT-R = Hopkins Verbal Learning Test – Revised; ITI = intertap interval; B = block; UPSIT = University of Pennsylvania Smell Identification Test; WAIS-III = Wechsler Adult Intelligence Scale – Third Edition; WASI = Wechsler Abbreviated Scale of Intelligence