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(A) Percent methylation of 10 CpG dinucleotides (# 3–12) in the PDYN promoter CpG island in two brain regions, the caudate and anterior cingulate cortex. (B) When stratified by HIV status, there was no difference in percent methylation of the CpG sites between HIV positive and HIV negative subjects. Methylation levels at each CpG site in each tissue are shown as mean ± SEM.
