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Transient expression of PDX-1 increases cell proliferation. HEK 293, MIA PaCa2 and HPDE cells were transfected with human PDX-1 with and without human PDX-1 shRNA. Transient burst expression of PDX-1 results in increased cell proliferation in HEK 293 (A), MIA PACa2 (B) and HPDE (C) cells (P<0.05, respectively). PDX-1 shRNA co-transfection blocks the effect of cell proliferation (white bar).
