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. Author manuscript; available in PMC: 2012 Feb 1.
Published in final edited form as: Biol Blood Marrow Transplant. 2010 Jul 24;17(2):157–166. doi: 10.1016/j.bbmt.2010.07.009

Table 4.

Pregnancy after hematopoietic-cell transplantation: distribution of age at transplant with dose of total body irradiation, dose of cyclophosphamide during conditioning and diagnosis

Characteristic Age at HCT in years, N (%)
<10 10-19 20-29 30-39 ≥40
Men who fathered a child after HCT, N
N 3 15 54 20 3
Dose of TBI
 No TBI 3 (100) 13 (87) 42 (78) 16 (80) 2 (67)
 <400 cGy 0 0 0 0 1 (33)
 400-799 cGy 0 1 (7) 2 (4) 0 0
 800-1199 cGy 0 1 (7) 8 (15) 4 (20) 0
 ≥1200 cGy 0 0 2 (4) 0 0
Conditioning regimen cyclophosphamide dose
 No cyclophosphamide 0 0 6 (12) 2 (10) 1 (33)
 ≤120 mg/kg 1 (33) 5 (33) 23 (44) 6 (30) 2 (67)
 121-200 mg/kg 1 (33) 8 (53) 20 (38) 12 (60) 0
 >200 mg/kg 1 (33) 2 (13) 3 (6) 0 0
Diagnosis
 Malignant disorder 1 (33) 6 (40) 40 (74) 15 (75) 3 (100)
 Non-malignant disorder 2 (66) 9 (60) 14 (26) 5 (25) 0
Women who reported pregnancy after HCT, N
N 5 36 34 7 0
Dose of TBI
 No TBI 3 (60) 33 (92) 28 (82) 6 (86) 0
 <400 cGy 0 0 3 (9) 0 0
 400-799 cGy 0 1 (3) 0 0 0
 800-1199 cGy 1 (20) 2 (6) 3 (9) 1 (14) 0
 ≥1200 cGy 1 (20) 0 0 0 0
Conditioning regimen cyclophosphamide dose
 No cyclophosphamide 0 1 (3) 5 (15) 1 (14) 0
 ≤120 mg/kg 2 (40) 5 (14) 6 (18) 2 (29) 0
 121-200 mg/kg 2 (40) 26 (72) 16 (47) 4 (57) 0
 >200 mg/kg 1 (20) 4 (11) 7 (21) 0 0
Diagnosis
 Malignant disorder 2 (40) 11 (30) 15 (44) 6 (86) 0
 Non-malignant disorder 3 (60) 26 (70) 19 (56) 1 (14) 0