Table 4.
Characteristic | Age at HCT in years, N (%) |
||||
---|---|---|---|---|---|
<10 | 10-19 | 20-29 | 30-39 | ≥40 | |
Men who fathered a child after HCT, N | |||||
N | 3 | 15 | 54 | 20 | 3 |
Dose of TBI | |||||
No TBI | 3 (100) | 13 (87) | 42 (78) | 16 (80) | 2 (67) |
<400 cGy | 0 | 0 | 0 | 0 | 1 (33) |
400-799 cGy | 0 | 1 (7) | 2 (4) | 0 | 0 |
800-1199 cGy | 0 | 1 (7) | 8 (15) | 4 (20) | 0 |
≥1200 cGy | 0 | 0 | 2 (4) | 0 | 0 |
Conditioning regimen cyclophosphamide dose | |||||
No cyclophosphamide | 0 | 0 | 6 (12) | 2 (10) | 1 (33) |
≤120 mg/kg | 1 (33) | 5 (33) | 23 (44) | 6 (30) | 2 (67) |
121-200 mg/kg | 1 (33) | 8 (53) | 20 (38) | 12 (60) | 0 |
>200 mg/kg | 1 (33) | 2 (13) | 3 (6) | 0 | 0 |
Diagnosis | |||||
Malignant disorder | 1 (33) | 6 (40) | 40 (74) | 15 (75) | 3 (100) |
Non-malignant disorder | 2 (66) | 9 (60) | 14 (26) | 5 (25) | 0 |
Women who reported pregnancy after HCT, N | |||||
N | 5 | 36 | 34 | 7 | 0 |
Dose of TBI | |||||
No TBI | 3 (60) | 33 (92) | 28 (82) | 6 (86) | 0 |
<400 cGy | 0 | 0 | 3 (9) | 0 | 0 |
400-799 cGy | 0 | 1 (3) | 0 | 0 | 0 |
800-1199 cGy | 1 (20) | 2 (6) | 3 (9) | 1 (14) | 0 |
≥1200 cGy | 1 (20) | 0 | 0 | 0 | 0 |
Conditioning regimen cyclophosphamide dose | |||||
No cyclophosphamide | 0 | 1 (3) | 5 (15) | 1 (14) | 0 |
≤120 mg/kg | 2 (40) | 5 (14) | 6 (18) | 2 (29) | 0 |
121-200 mg/kg | 2 (40) | 26 (72) | 16 (47) | 4 (57) | 0 |
>200 mg/kg | 1 (20) | 4 (11) | 7 (21) | 0 | 0 |
Diagnosis | |||||
Malignant disorder | 2 (40) | 11 (30) | 15 (44) | 6 (86) | 0 |
Non-malignant disorder | 3 (60) | 26 (70) | 19 (56) | 1 (14) | 0 |