Table 2.
Gene | Polymorphisms | Allelic frequencies (variant allele) | Genotype distributions | ||
---|---|---|---|---|---|
wt/wt | wt/m | m/m | |||
ABCB1 | 1236 C>T | 0.427 | 75/227 | 110/227 | 42/227 |
2677 G>T | 0.427 | 75/227 | 110/227 | 42/227 | |
3435 C>T | 0.509 | 59/227 | 105/227 | 63/227 | |
CYP3A4 | −392 A>G (CYP3A4*1B) | 0.037 | 210/227 | 17/227 | 0/227 |
CYP3A5 | 6986 A>G (CYP3A5*3) | 0.923 | 0/227 | 35/227 | 192/227 |
wt: wild type, m: mutated