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. Author manuscript; available in PMC: 2011 Jan 10.
Published in final edited form as: Clin Pharmacol Ther. 2010 May 26;88(1):95–100. doi: 10.1038/clpt.2010.62

Table 2.

Frequency and distribution of the studied polymorphisms in donors (n=227)

Gene Polymorphisms Allelic frequencies (variant allele) Genotype distributions
wt/wt wt/m m/m
ABCB1 1236 C>T 0.427 75/227 110/227 42/227
2677 G>T 0.427 75/227 110/227 42/227
3435 C>T 0.509 59/227 105/227 63/227
CYP3A4 −392 A>G (CYP3A4*1B) 0.037 210/227 17/227 0/227
CYP3A5 6986 A>G (CYP3A5*3) 0.923 0/227 35/227 192/227

wt: wild type, m: mutated