. Author manuscript; available in PMC: 2011 Jan 10.

Published in final edited form as: Clin Pharmacol Ther. 2010 May 26;88(1):95–100. doi: 10.1038/clpt.2010.62

Table 4.

Multivariate analysis (Cox Model) for risk of graft loss (taking in account either the three ABCB1 genotypes separately or the corresponding haplotype).

Variable	Category	Adjusted Hazard ratio	Adjusted CI 95%	p
*ABCB1 2677 G>T*	TT vs GG	12.048	2.392–58.823	0.0025
*ABCB1 2677 G>T*	GT vs GG	4.673	1.020–21.276	0.0471
*Acute rejection*	≥1 vs 0	3.077	1.213–7.812	0.0178
*ABCB1 haplotype*	TTT/TTT vs other/other	9.346	2.278–38.461	0.0019
*ABCB1 haplotype*	TTT/other vs other/other	3.322	0.918–12.048	0.0671
*Acute rejection*	≥1 vs 0	2.849	1.129–7.194	0.0266