Figure 5.

Conceptual model of the AtGRP7 feedback loop. AtGRP7 transcript oscillations are under control of the core oscillator [14,60]. Furthermore, AtGRP7 expression is influenced by environmental stimuli including cold. AtGRP7 itself negatively autoregulates at the post-transcriptional level. Downstream targets of AtGRP7 include circadian transcripts that are affected in a time-of-day dependent manner: AtGRP7 negatively affects steady-state abundance of evening-phased transcripts and positively affects steady-state abundance of late night/morning genes. Further, transcripts responsive to environmental signals are prevalent among AtGRP7 targets. Arrows indicate activation, blunt lines indicate negative interaction.