Table 1.
Pre-MI |
Post-MI |
|||||||
---|---|---|---|---|---|---|---|---|
NDV | NDB | DV | DB | NDV | NDB | DV | DB | |
LVAWs (mm) | 1.50±0.05 | 1.43±0.04 | 1.36±0.04 | 1.40±0.07 | 0.33±0.07δδ | 0.46±0.07δδ* | 0.28±0.05δδ | 0.42±0.05δδ# |
LVAWd (mm) | 0.90±0.04 | 0.89±0.04 | 0.90±0.04 | 0.91±0.04 | 0.32±0.05δδ | 0.38±0.05δδ* | 0.26±0.03δδ* | 0.35±0.06δδ# |
LVPWs (mm) | 1.27±0.08 | 1.33±0.04 | 1.30±0.10 | 1.30±0.09 | 1.07±0.31δ | 1.36±0.21* | 1.04±0.12δ | 1.33±0.11# |
LVPWd (mm) | 0.95±0.07 | 0.95±0.07 | 0.95±0.06 | 0.90±0.04 | 0.8±0.22 | 0.93±0.11 | 0.80±0.14 | 1.06±0.13δ# |
LVESD (mm) | 2.30±0.44 | 2.31±0.44 | 2.40±0.19 | 2.33±0.26 | 5.28±0.45δδ | 4.78±0.31δδ* | 5.90±0.29δδ | 5.06±0.19δδ# |
LVEDD (mm) | 3.30±0.30 | 3.30±0.31 | 3.20±0.30 | 3.40±0.10 | 5.69±0.37δδ | 5.71±0.31δδ | 6.20±0.26δδ | 5.44±0.29δδ# |
LVESV (μl) | 15.8±1.4 | 15.4±1.9 | 16.8±2.8 | 16.3±1.2 | 123.7±33.1δδ | 92.8±10.7δδ* | 164.4±20.7δδ* | 110.3±13.7δδ# |
LVEDV (μl) | 59.3±2.7 | 56.0±2.0 | 60.3±3.7 | 61.2±2.3 | 157.9±26.1δδ | 148.4±17.2δδ | 185.0±19.5δδ* | 150.9±14.0δδ# |
LVSV (μl) | 43.5±2.7 | 40.6±3.5 | 43.5±4.1 | 44.8±2.6 | 34.3±11.6δ | 55.6±17.2δ* | 20.6±7.6δδ* | 40.6±6.7# |
LVEF (%) | 70.5±6.6 | 70.9±4.5 | 70.8±3.0 | 70.5±4.1 | 22.7±9.5δδ | 36.9±9.3δδ* | 11.9±4.3δδ* | 25.3±4.2δδ# |
LVFS (%) | 38.7±2.2 | 38.3±2.7 | 38.4±2.4 | 38.5±1.7 | 11.3±5.6δδ | 16.5±4.1δδ* | 7.7±3.2δδ | 11.6±2.3δδ# |
HR (bpm) | 497±13 | 498±13 | 482±31 | 488±22 | 532±19δ | 544±20δ | 489±19* | 504±12 |
CO (mL/min) | 21.7±1.9 | 22.9±1.8 | 20.9±2.3 | 21.9±1.6 | 18.1±5.7 | 24.2±9.3* | 10.2±3.9δδ* | 20.5±3.6# |
E (mm/s) | 941±77 | 943±77 | 769±52γ | 862±59δ† | 638±131δδ | 680±93δδ | 598±83δδ | 638±88δδ |
A (mm/s) | 438±33 | 440±21 | 680±65γγ | 500±56δ† | 804±91δδ | 698±53δδ* | 944±86δδ* | 901±66δδ |
E/A | 2.15±0.19 | 2.17±0.17 | 1.12±0.11γγ | 1.73±0.24† | 0.80±0.17δδ | 0.95±0.14δδ* | 0.64±0.11δδ* | 0.71±0.09δδ |
Data are presented as mean±SD. NDV, non-diabetic vehicle-treated; NDB, non-diabetic BFT-treated; DV, diabetic vehicle-treated; DB, diabetic BFT-treated; LVAWs, LV anterior wall, end-systole; LVAWd, LV anterior wall, end-diastole; LVPWs, LV posterior wall, end-systole; LVPWd, LV posterior wall, end-diastole; LVESD, LV end-systolic diameter; LVEDD, LV end-diastolic diameter; LVESV, LV end-systolic volume; LVEDV, LV end-diastolic volume; LVSV, LV stroke volume; LVEF, LV ejection fraction; LVFS, LV fractional shortening; HR, heart rate; CO, cardiac output; E, mitral valve velocity during early diastolic filling; A, mitral valve velocity during atrial contraction
P<0.01 and
P<0.001 versus NDV pre-MI;
P<0.01 versus DV pre-MI.
P<0.01 and
P<0.001 versus corresponding group pre-MI;
P<0.01 versus NDV post-MI;
P<0.01 versus DV post-MI.