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. 2001 Feb 20;98(5):2577–2581. doi: 10.1073/pnas.041608298

Figure 1.

Figure 1

Vα14 NKT cells are required for anti-LFA-1/ICAM-1- or anti-B7–1/B7–2-induced cardiac allograft tolerance. BALB/c hearts were transplanted into WT or NKT KO B6 mice. (A) Some recipients received anti-LFA-1/ICAM-1 mAbs for the first 5 days after transplantation. Some NKT KO recipients were transferred with Vα14 NKT cells before transplantation. (B) Both WT and NKT KO recipients received anti-B7–1/B7–2 mAbs for the first 5 days after transplantation. Similar results were obtained in two independent experiments.