Table 2.

Number of drugs within % error in the prediction of morphine clearance in children across different age groups

Age group	≤30%	≤50%	51–99%	≥100	≥1000	%HE*
Pre-term: (n = 75)
Exp (0.75)	0	0	0	8	67	8494
Maturation	18	25	21	27	2	1090
Pre-term:†
Maturation	29	45	18	12	0	626
Term: (n = 33)
Exp (0.75)	1	2	0	22	9	6818
Maturation	6	16	4	12	1	1166
1 week to 2 months (n = 12)
Exp (0.75)	5	7	2	3	0	286
Maturation	2	7	5	0	0	73
>2–10 months (n = 15)
Exp (0.75)	2	5	3	7	0	844
Maturation	7	11	2	2	0	381
3.1–5 years (n = 12)
Exp (0.75)	6	9	3	0	0	59
Maturation	6	9	3	0	0	59
Total (exp 0.75)	14 (10%)	23 (16%)	8 (5%)	40 (27%)	76 (52%)	8494
Total maturation model‡	50 (34%)	88 (60%)	32 (22%)	26 (18%)	1 (<1%)	1166

^*%HE = % highest error.

^†With adjustment factor of 0.61.

^‡Numbers in parenthesis are the percent of the total observations. n = 147.