Table 3.

Selected B cell related genes^*

Probe ID no.‡	Gene symbol‡	p§	Controls	Fold change†
				Patients with persistent oligoarticular JIA	Patients with RF-negative polyarticular JIA	Patients with systemic JIA
1558662_s_at	BANK1	0.003	1.17	1.74	1.71	2.24
222891_s_at	BCL11A	0.004	1.18	1.43	1.24	1.73
1553369_at	BCNP1	0.009	1.13	1.97	1.67	2.39
207655_s_at	BLNK	0.005	1.23	1.65	1.59	2.1
1554343_a_at	BRDG1	0.01	1.18	1.68	1.61	2.28
236226_at	BTLA	0.04	1.03	1.62	1.6	1.52
206398_s_at	CD19	0.004	1.21	2.16	2.07	2.75
204581_at	CD22	0.008	1.07	1.83	1.53	2.05
205692_s_at	CD38	0.003	1.5	1.61	1.48	1.44
215346_at	CD40	0.03	1.13	1.38	1.22	1.46
215925_s_at	CD72	0.03	1.17	2.01	2.23	3.14
205049_s_at	CD79A	0.04	1.24	1.62	1.56	2.23
205297_s_at	CD79B	0.03	1.25	1.62	1.59	1.95
209583_s_at	CD200	0.04	1	1.74	1.5	1.71
232204_at	EBF	0.008	1.15	1.81	1.4	1.86
201025_at	EIF5B	0.02	0.97	1.2	1.1	0.97
209762_x_at	SP110	0.03	1.17	1.24	1.1	1.19
210776_x_at	TCF3	0.003	1.02	1.17	1.14	1.08

^*See Table 1 for definitions.

^†Ratio of geometric mean of expression in patients with early-onset disease:geometric mean of expression in patients with late-onset disease, or ratio of geometric mean of expression in younger controls (age <6 years at time of sampling):geometric mean of expression in older controls (age ≥ 6 years at time of sampling).

Ratio of geometric mean of expression in patients with early-onset disease:geometric mean of expression in patients with late-onset disease, or ratio of geometric mean of expression in younger controls (age <6 years at time of sampling):geometric mean of expression in older controls (age ≥ 6 years at time of sampling).

^‡Affymetrix HG-U133 Plus 2.0 GeneChips probe set ID numbers and gene symbols.

^§By false discovery rate adjusted t-test comparing samples from patients with early- and late-onset oligoarticular disease.