Table 2.
Platelet characteristics. Data are given as mean ± SEM (range)
17β-estradiol ≤20 pg/ml (n = 21) | 17β-estradiol > 40 pg/ml (n = 11) | |
---|---|---|
Platelets/μl × 103 | 241 ± 10 | 243 ± 20 |
P-selectin-positive (%) | ||
Basal | 4.4 ± 2.1 | 2.2 ± 0.4 |
sTRAP | 93 ± 0.6 | 92 ± 0.7 |
ADP | 67 ± 2.8 | 70 ± 3.1 |
PAC-1-positive (%) | ||
Basal | 1.0 ± 0.1 | 0.8 ± 0.2 |
sTRAP | 9.0 ± 1.3 (2–21) | 19 ± 4.6 (1–50)* |
ADP | 67 ± 2.9 (31–88) | 82 ± 2.8 (62–94)* |
sTRAP, thrombin receptor agonist peptide; ADP, adenosine diphosphate
Significantly different from low estrogen, p < 0.05