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. Author manuscript; available in PMC: 2012 Jan 1.
Published in final edited form as: Cancer Prev Res (Phila). 2010 Nov 30;4(1):43–50. doi: 10.1158/1940-6207.CAPR-10-0151

Table 3. Multivariable logistic regression analyses: Effect of emphysema on lung cancer risk.

Category Number of cases affected/Number of controls affected Odds Ratio 95% Confidence Interval
Emphysema
 Clinically diagnosed emphysema 218/22 13.37 8.29 - 21.56
 CT-diagnosed emphysema (%)
  >0 409/261 2.79 2.05 - 3.81
  ≥5 226/84 3.80 2.78 - 5.19
  ≥10 143/51 3.33 2.30 - 4.82

Clinically diagnosed emphysema: adjusted for age, pack-years, other lung disease (including chronic bronchitis and unspecified COPD), and family history of lung cancer.

CT-diagnosed emphysema: adjusted for pack-years, other lung disease (including chronic bronchitis and unspecified COPD), and family history of lung cancer.

All P values were <0.0001.

Results by adjusting for years smoked, cigarettes per day, other lung disease (including chronic bronchitis and unspecified COPD), and family history of lung cancer remained very similar (data not shown).