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. 2010 Dec 1;4(1):4–16. doi: 10.1007/s12410-010-9060-6

Table 1.

Physical and chemical properties and pharmacokinetics of Gd micelles

Formulation Size, nm r1, 60 MHz (s−1 mM−1) Blood half-life, h %ID in liver of apoE−/− mice at 24 h
apoE−/− mice Wild-type mice
MDA2-micelles 22 ± 2 9.3 14.3* 1.7 18 ± 4
IK17-micelles 16 ± 3 10.5 16.5* 1.8 18 ± 4
E06-micelles 16 ± 3 10.8 20.1* 1.7 32 ± 2
IgG-micelles 16 ± 4 10.4 1.4 1.3 18 ± 3
Untargeted micelles 14 ± 2 11.6 1.5 1.5 12 ± 3

*P < 0.001 compared to wild-type mice