Table 1.

Chemotherapy protocols.

OPEC regimen	Dose	Route and duration of administration	Timing
Vi Vincristine	1.5 mg/m2	i.v.	Day 1
Cisplatin	80 mg/m2	i.v. (6 hours infusion)	Day 2
Etoposide	200 mg/m2	i.v. (2 hours infusion)	Day 4
Cyclophosphamide	600 mg/m2	i.v. (2 hours infusion)	Day 1
Alternating every 3 weeks with OJEC regimen
Vincristine	1.5 mg/m2	i.v.	Day 1
Carboplatin	500 mg/m2	i.v. (6 hour infusion)	Day 1
Etoposide	200 mg/m2	i.v. (2 hours infusion)	Day 1
Cyclophosphamide	600 mg/m2	i.v. (2 hours infusion)	Day 1