Table 1.
In vivo growth of PPARδ null cells
| Experiment no. | Frequency | All tumors | Established tumors |
|---|---|---|---|
| 1 (28 days) | |||
| PPARδ +/+ | 2/2 | 1218 ± 1095 | 1218 ± 1095 |
| PPARδ +/− | 2/2 | 987 ± 49 | 987 ± 49 |
| PPARδ −/− clone 1 | 1/2 | 2 ± 2 | 4 ± NA |
| 2 (30 days) | |||
| PPARδ +/+ | 4/4 | 1306 ± 680 | 1306 ± 680 |
| PPARδ +/− | 4/4 | 2333 ± 803 | 2333 ± 803 |
| PPARδ −/− clone 1 | 4/4 | 374 ± 46 | 374 ± 46 |
| 3 (33 days) | |||
| PPARδ +/+ | 10/10 | 1617 ± 248 | 1617 ± 248 |
| PPARδ −/− clone 1 | 4/10 | 271 ± 107 | 609 ± 90 |
| 4 (34 days) | |||
| PPARδ +/+ | 5/5 | 1922 ± 823 | 1922 ± 823 |
| PPARδ −/− clone 2 | 2/5 | 86 ± 64 | 214 ± 115 |
| 5 (34 days) | |||
| PPARδ +/+ | 6/6 | 673 ± 80 | 673 ± 80 |
| PPARδ +/− | 5/5 | 732 ± 164 | 732 ± 164 |
| PPARδ −/− clone 1 | 2/5 | 56 ± 48 | 141 ± 66 |
| PPARδ −/− clone 2 | 1/5 | 49 ± 49 | 243 ± NA |
In vivo growth of PPARδ null cells. Five experiments are presented measuring the growth of various PPARδ null lines as described in Materials and Methods. The Frequency column indicates the fraction of inoculation sites in which a tumor grew. The All tumors column indicates the average volume (mm3) ±SE of tumors for all inoculation sites, whereas the Established tumors column indicates the average volume (mm3) ±SE for only those tumors that were clearly detectable on the date of the final measurement, as indicated in parentheses next to the experiment number. NA, not applicable.