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. 2011 Jan 10;6(1):e15864. doi: 10.1371/journal.pone.0015864

Table 1. FACS profile for cell cycle analysis with ovarian cancer cells that were grown under cell culture conditions consisting of increasing serum and O2 concentration.

Cells Serum G1 S G2
3% O2 21% O2 p-value 3% O2 21% O2 p-value 3% O2 21% O2 p-value
2% 66.8±0.9 62.5±0.2 0.0011 25.6±1 27.5±0.1 0.02800 7.6±0.4 9.96±0.1 0.0007
A2780 6% 76.9±2.1 64.3±0.7 0.0006 17.5±0.9 29±0.1 <0.0001 5.6±1.4 6.7±0.6 ** NS **
10% 84.1±3.2 69.5±1.4 0.0028 14.3±1.9 26.5±1.3 0.0080 1.5±1.3 4±0.7 0.0411
2% 66.4±0.7 60.2±0.4 0.0001 25.8±0.2 29.3±0.6 0.0006 7.7±0.5 10.4±0.3 0.0017
OVCAR5 6% 79±1.5 70.2±0.5 0.0014 17.4±1.5 25.1±0.9 0.0015 3.4±0.4 4.7±0.6 ** NS **
10% 90.6±1.2 84±1.6 0.0077 8.2±1.4 14.6±1.5 0.0052 1.1±0.1 1.2±2.1 ** NS **
2% 74.7±10.7 69±1 ** NS ** 15.5±2.5 23.7±0.6 0.0052 13.7±2.3 6±0 0.0043
OVCAR8 6% 66±1 59±1 0.0010 25.7±1.5 30±0 0.0079 7±0 9.7±0.6 0.0013
10% 69±4.6 61.7±1.5 0.0582 24.3±1.5 30.7±1.2 0.0045 5.3±3.8 6.3±0.6 ** NS **
2% 69.3±1.5 58.7±2.1 0.0020 25±1 34±1 0.0003 4.3±1.5 5.7±1.5 ** NS **
HeyA8 6% 62.7±0.6 53.7±1.5 0.0006 30.3±1.2 37.3±2.5 0.0118 5.3±0.6 8±3.5 ** NS **
10% 61.7±1.2 50.3±2.3 0.0016 30.7±1.2 37.3±1.2 0.0021 6.7±2.3 11±1.6 ** NS **
2% 80±1.7 72.3±1.5 0.0045 15±0 18.7±1.5 0.0141 5±1.7 8±1 ** NS **
HOC8 6% 80.3±1.2 72.7±1.2 0.0012 15.3±1.5 22.7±1.5 0.0041 3.3±1.5 3.7±1.5 ** NS **
10% 78.7±2.5 73.3±0.6 0.0232 16.3±0.6 23.7±0.6 <0.0001 4.3±2.5 3±1 ** NS **
2% 74±2 62.1±1.7 0.0014 13.5±3.5 27.7±1.2 0.0026 12±2 10.3±2.5 ** NS **
SKOV3 6% 76.7±1.5 65.3±3.2 0.0052 14±1 25.7±1.5 0.0003 9.3±1.5 9±2 ** NS **
10% 80.3±1.2 68±1.7 0.0005 12.7±1.5 26±1 0.0002 7±1 6.3±0.6 ** NS **

**NS** “Not Significant”