Table 1.

Combinations of settings used; bold indicates baseline settings.

	Number of cases	Region	Probability Model	Maximum cluster size
Spatial combinations	600	NE counties	Poisson	50% population
	600	NE counties	Bernoulli	50% population
	600	NE counties	Poisson	1 county
	600	US 3-digit zip codes	Poisson	50% population
	6	NE counties	Poisson	50% population
	6000	NE counties	Poisson	50% population
	60000	NE counties	Poisson	50% population
Space-time combinations	600	NE counties, 60 days	Poisson	50% population, 7 days
	600	NE counties, 60 days	Space-time permutation	50% population, 7 days