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. 2010 Dec 14;11:701. doi: 10.1186/1471-2164-11-701

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Copyright ©2010 Etcheverry et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (<url>http://creativecommons.org/licenses/by/2.0</url>), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Analysis of the hypermethylated CpGs located within PRC2-targeted promoters. (A) Heatmap of the hypermethylated CpGs located within PRC2-targeted promoters. Samples are ranked horizontally as a function of their mean β-values. Two clusters representing extreme methylation changes (Δβ) relative to control samples (N) are framed. (B) EZH2 and DNMT3A expression level in control samples, GBM samples, the low- and the high-Δβ clusters. The expression values presented are normalized and log-transformed intensities.