Table 1.

VEGF-induced angiogenesis and vascular permeability in iNOS mutant mice

Genotype	Angiogenesis rate, % per day	Vessel density,‡ cm/cm2	Vessel diameter,‡ μm	Vascular permeability, 10−7 cm/s
WT (n = 10)†	6.1  ± 0.2	67.0  ± 3.7	12.0  ± 0.3	4.4  ± 1.2
iNOS−/− (n = 8)†	5.5  ± 0.3	44.2  ± 6.0*	11.6  ± 0.4	4.1  ± 1.4

^*, P < 0.05 as compared with WT. 

^† C57BL/6 single strain background. 

^‡ Total of 50 and 40 locations were determined for WT and iNOS^−/−, respectively.