Figure 3.

RT-PCR of cDNA prepared from uterine RNA isolated from WT, KIKO, or αERKO mice treated with saline vehicle (V), E₂, BPA, or HPTE for 2 hr. Abbreviations: Stat5a, signal transducer and activator of transcription 5A; Cdkn1a (p21), cyclin-dependent kinase inhibitor 1A (P21); Nr4a1, nuclear receptor subfamily 4, group A, member 1; Inhbb, inhibin βb; Wnt4, wingless-related MMTV integration site 4; Fos, FBJ osteosarcoma oncogene; Mad2l1, MAD2 mitotic arrest deficient-like 2 (yeast); Errfi1 (MIG6), ERBB receptor feedback inhibitor 1; Cyr61, cysteine rich protein 61; Ppp2r2c (PP2A), protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), gamma isoform; Sox8, SRY-box containing gene 8; Gadd45g, growth arrest and DNA-damage-inducible 45. Values are calibrated relative to ribosomal protein L7 (PL-7) and are plotted relative to WT vehicle levels for each transcript; results were analyzed by two-way ANOVA with a post t-test.

^ap < 0.01 relative to E₂. **p < 0.01 relative to the vehicle within the genotype.