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. Author manuscript; available in PMC: 2011 Jan 10.
Published in final edited form as: Cell Calcium. 2009 Jan 7;45(3):284–292. doi: 10.1016/j.ceca.2008.11.006

Fig. 3.

Fig. 3

Ca2+ chelation within nuclei or extra-nuclear cytoplasm inhibits LX-2 cell proliferation. (A) Proliferation in the presence of serum. LX-2 cells were either untransfected or transfected with DsRed, PV-NLS-DsRed, or PV-NES DsRed, and proliferation was determined by BrdU uptake. Relative to control, proliferation of cells transfected with either PV-NLS-DsRed or PV-NES-DsRed was diminished (*p < 10−5; n = 10 for each condition). (B) Proliferation in the absence of serum. LX-2 cells were transfected identically to those in (A); however, cells were grown in serum-free media. As seen, no change in proliferation was noted.