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. Author manuscript; available in PMC: 2011 Jan 10.
Published in final edited form as: Cell. 2009 Oct 16;139(2):312–324. doi: 10.1016/j.cell.2009.07.050

Figure 1.

Figure 1

A) Structure of Pol γA The pol domain shows a canonical ‘right-hand’ configuration with thumb (green), palm (red) and fingers (blue) subdomains, and the exo domain (grey). The spacer domain (orange) presents a unique structure and is divided into two subdomains. Domains are shown in a linear form where the N-terminal domain contains residues 1-170; exo: 171-440; spacer: 476-785; pol: 441-475 and 786-1239. All figures are made with Pymol (DeLano, 2002). B) Structure of the heterotrimeric Pol γ holoenzyme containing one catalytic subunit Pol γA (orange) and the proximal (green) and distal (blue) monomers of Pol γB.