. Author manuscript; available in PMC: 2012 Feb 1.

Published in final edited form as: Biochim Biophys Acta. 2010 Oct 23;1814(2):388–395. doi: 10.1016/j.bbapap.2010.10.005

Table 1.

Summary of aggregation parameters

Protein	^aK_crit (nM)	^ak_e₋ (s⁻¹)	^ak_e₊ (mM⁻¹s⁻¹)	Lag Time (h)	K_n (mM)
2N4R	186 ± 25	0.020 ± 0.001	105 ± 15	0.81 ± 0.06	21.7
T212E	84 ± 28^**	0.011 ± 0.001^**	133 ± 46	0.28 ± 0.05^**	5.1

Overall constants reflecting events at both filament ends

^**

p < 0.01 versus 2N4R tau