Intracellular Ca2+ regulating proteins in myocardium from lean and ob/ob obese mice treated with or without TUDCA (50 mg/kg for 5 wks, p.o.). A: Representative gel blots depicting expression of SERCA2a, Na+-Ca2+ exchanger (NCX), phospholamban (PLB) and GAPDH (loading control) using specific antibodies; B: SERCA activity measured by the SERCA-dependent 45Ca2+ uptake; C SERCA2a expression; D: Na+-Ca2+ exchanger expression; and E: Phospholamban expression. Mean ± SEM, n = 4–5, * p < 0.05 vs. lean group, # p < 0.05 vs. obese group.