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. Author manuscript; available in PMC: 2012 Jan 1.
Published in final edited form as: Antiviral Res. 2010 Nov 10;89(1):26–34. doi: 10.1016/j.antiviral.2010.11.002

Fig. 4. Combination of imino sugar and ribavirin synergistically inhibited DENV infection in vitro.

Fig. 4

Antiviral activities of indicated doses of CM-10-18 and ribavirin, either alone or in combination in a checkboard dilution format, were performed with CFI assay in A549 cells. (A) Effect on DENV E protein, shown as percentage of no treatment control; (B) Synergy analysis was performed with MacSyngergy II. The peak above the surface represents the degree of synergy with 95% confidence interval, calculated from 8 independent experiments.