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. Author manuscript; available in PMC: 2012 Jan 1.
Published in final edited form as: Antiviral Res. 2010 Nov 10;89(1):26–34. doi: 10.1016/j.antiviral.2010.11.002

Fig. 5. Ribavirin significantly improved imino sugar's antiviral activity in DENV infected mice.

Fig. 5

AG129 mice were treated with (A) either 40mg/kg of ribavirin, 75mg/kg of CM-10-18 or a combination of the two compounds; (B) 40mg/kg of ribavirin, doses of CM-10-18, or combination of two compounds, as indicated. PBS was given to control mice. 3 days after infection, the blood samples were drawn to determine virus titer by plaque assay. Values represent average and standard deviation from results obtained from 6 mice per treatment group. P values were calculated using student t test. * indicate P values compared to PBS control.