Table 1.

In vitro pharmacological characteristics of the receptor agonists

	Cotransfection efficacy, %			Binding Ki, nM
	RXRα*	PPARγ†	PPAR‡	RXRα	PPARγ
LG100364	77	46		5.3
LG101305	89	38		3.7
BRL49653 (Rosiglitazone)	1	100	9		22
GW2331	2	125	100

^*Efficacy relative to all-trans retinoic acid. 

^† Efficacy relative to BRL49653. 

^‡ Efficacy relative to GW2331.