Table 2.
A summary of incidence of pathological phenotypes in a variety of PtenshRNA mouse organs
| Tissues | Pathology | No. observed | No. of PtenshRNA mice analyzed |
| Prostate | Atypical hyperplasia (AH) and Prostatic intraepithelial neoplasia (PIN) | 6 | 43 |
| Uterus | Complex atypical hyperplasia | 1 | 33 |
| Adrenal | Pheochromocytoma | 2 | 70 |
| Lymph node | Lymphoid hyperplasia | 50 | 75 |
| Spleen | Splenomegaly with folicular hyperplasia (FH) or epithelial-mesenteric hyperplasia (EMH) | 48 | 72 |
| Salivary gland | Sialadenitis (Inflammation of the salivary gland) | 24 | 68 |
| Skin | Severe inflammatory ulcers, sebacious gland adenoma, sebacious cyst, dermoid cyst. | 23 | 76 |
| Brain | 0 | 77 |
A total of 77 mice of both sexes from PtenshRNA lines PtenshRNA4, PtenshRNA5 and PtenshRNA21 were analyzed histopathologically. Shown in the table are the total number of specimen analyzed and number with indicated phenotype.