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. Author manuscript; available in PMC: 2011 Dec 1.
Published in final edited form as: J Neural Eng. 2010 Nov 17;7(6):066008. doi: 10.1088/1741-2560/7/6/066008

Figure 3.

Figure 3

Comparison of charge and energy required to intracellularly activate a single myelinated axon. Current was injected into the central node of Ranvier via a simulated current clamp using 8 different waveforms (inset). Upper left: Strength-duration curve. Upper Right: Charge required for activation. Lower left: Energy required for activation. Lower right: Energy versus charge thresholds. Gaussian and centered triangular waveforms demonstrate minimal energy thresholds, and have significant overlap.