Figure 1.

Intravital fluorescence imaging of Bx-PC-3-GFP human pancreas cancer angiogenesis. (A) Orthotopic tumor. (B) Metastatic lesion in spleen. The GFP-expressing human tumor was transplanted to nude mice by SOI and intravitally imaged 50 days later, as described in Materials and Methods. (Bar = 200 μm.)