Table 2.

Recommendations for Detection of Chromosomal Mosaicism and SGV

Source	Area of Application	Detection Rate	Amount of Cells to Score
Hsu et al., 1992 [49]	Prenatal diagnosis by cytogenetic techniques	0.5% (1 cell)*	200
Caudill et al., 2005 [50]	Prenatal diagnosis by cytogenetic techniques	15%	15-30
Vorsanova et al., 2005 [12]	Fetal aneuploidy by molecular cytogenetic techniques	<5%	300-500
Yurov et al., 2005 [39]; 2007 [29, 41]; 2008 [42]; Iourov et al., 2006 [3]; 2009 [38].	Chromosome abnormalities or SGV by molecular cytogenetic techniques	<0.1%	1000-10000
Iourov et al., 2009 [36, 37]	Chromosome instability or SGV by molecular cytogenetic techniques	0.1-1%	1000-10000
Iourov et al., 2006 [40]; 2009 [38]	Chromosome abnormalities or SGV by molecular cytogenetic techniques	<0.5% (1 cell)*	>100
Wiktor et al., 2009 [51]	Sex chromosome aneuploidy by cytogenetic techniques	>3% (1 cell)	20-30

^*– pseudomosaicism.