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. Author manuscript; available in PMC: 2011 Oct 29.
Published in final edited form as: Chem Biol. 2010 Oct 29;17(10):1101–1110. doi: 10.1016/j.chembiol.2010.07.017

Figure 2. Structures of WTA substrates and intermediates.

Figure 2

The structures of the CDP-glycerol (1) and CDP-ribitol (2) donor and lipid acceptor substrates 3, 4, 5, 6, and 7. The natural acceptor substrates contain an undecaprenyl chain. Substrates having the “a” suffix contain a neryl chain and were used for LC/MS analysis; substrates having the “b” suffix contain a farnesyl chain and were used for PAGE analysis. Synthesis of substrates and incorporation of [14C] radiolabels for PAGE analysis were carried out as described previously (Brown et al., 2008).