Figure 2. Exposure to uranium does not cause apoptosis regardless of p53 status.
Hct116 (p53 +/+) (A) or Hct116 (p53 −/−) (B) cells were grown to 85% confluence and then exposed to either uranium acetate (UA) or uranium nitrate (UN). The cells were incubated with the uranium compounds for 24 h before harvesting and analyzing by flow cytometry. The graph depicts the fraction of viable cells and each point represents the average of 4500 events.