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. 2010 Dec 9;1(8):734–740. doi: 10.18632/oncotarget.208

Figure 2: Glutaminase inhibition prevents Rho GTPase driven transformation.

Figure 2:

NIH-3T3 mouse fibroblasts in 10 cm plates were transfected with pZIPneoDbl and allowed to grow for 10 days in the presence of DMSO only (control), 5 M of the inactive 968 analog 335 (CAS registry number 22949-42-4), or 5 M 968 (CAS registry number 311795-38-7), after which the plates were fixed and stained with crystal violet. Structures of the inactive and active compounds are shown below treated cell samples.