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. Author manuscript; available in PMC: 2011 Nov 24.
Published in final edited form as: Cell. 2010 Nov 24;143(5):802–812. doi: 10.1016/j.cell.2010.10.002

Figure 3. Sirt3 Increases the Ratios Of GSH:GSSG in Mitochondria During CR.

Figure 3

(A–C) Ratios of GSH:GSSG (A), GSSG (B), and GSH (C) were measured in the inner ear, brain (neocortex), and liver from control diet and calorie restricted WT and Sirt3−/− mice at 5 months of age (n = 4–5). *Significantly different from 12- or 5-month-old WT mice (P < 0.05). Data are means ± SEM.