(A) Hiologic damage score. Hiologic damage was assessed semiquantitatively based on the extent of sinusoidal congestion, sinusoidd derangement, hepatocyte injury, and hepatocyte necrosis. Each index was scored as none = 0; mild = 1; moderate = 2; and severe = 3. (B) Number of infiltrated polymorphonuclear cells (PMNs) in liver tissue. Data are expressed as mean ± SEM per 1,000 hepatocyte nuclie. Group CT, untreated control (n = 10); group LA, treated with L-arginine (n = 5); group FK, treated with FK409 (n = 5). *p < 0.05 versus group CT.