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. Author manuscript; available in PMC: 2011 Jan 11.
Published in final edited form as: J Am Coll Surg. 1999 Jan;188(1):43–52. doi: 10.1016/s1072-7515(98)00259-2

Table 2.

Tissue Concentrations of Adenine Nucleotides (nmol/g Tissue) During Ischemia and After Reperfusion

Examination time ATP ADP AMP TAN Energy
charge
Before ischemia
 CT 2,666.2 ± 310.6 894.0 ± 11.2 213.6 ± 29.0 3,773.7 ± 314.1 0.82 ± 0.02
End of ischemia
 CT 236.9 ± 45.2 335.0 ± 29.1 1,147.1 ± 107.2 1,718.9 ± 147.8 0.23 ± 0.03
 LA 452.1 ± 187.3 665.0 ± 236.0 1,889.1 ± 185.9* 2,925.7 ± 560.7* 0.23 ± 0.04
 FK 338.9 ± 104.7 491.1 ± 141.9 1,706.6 ± 53.0* 2,536.8 ± 221.0 0.20 ± 0.05
15 min after reperfusion
 CT 846.8 ± 170.2 409.9 ± 65.6 160.0 ± 17.8 1,416.8 ± 234.0 0.72 ± 0.04
 LA 2,071.8 ± 338.6* 738.3 ± 146.7 276.4 ± 55.2 3,086.5 ± 365.8* 0.78 ± 0.04
 FK 2,041.2 ± 593.3* 866.0 ± 170.5* 431.8 ± 121.5* 3,339.2 ± 424.5* 0.74 ± 0.08
60 min after reperfusion
 CT 1,227.2 ± 138.3 329.4 ± 33.4 112.2 ± 14.7 1,668.8 ± 160.1 0.83 ± 0.02
 LA 2,181.4 ± 504.1 768.1 ± 94.5* 205.6 ± 47.7* 3,155.1 ± 527.1* 0.80 ± 0.02
 FK 2,314.6 ± 401.5* 774.6 ± 105.8* 274.2 ± 24.5* 3,363.4 ± 440.8* 0.78 ± 0.02
*

p < 0.05 versus group CT. Data are expressed as mean ± SEM.

ADP, adenosine diphosphate; AMP, adenosine monophosphate; ATP, adenosine triphosphate; CT, untreated control (n = 10); FK, group treated with FK409 (n = 5); LA, group treated with L-arginine (n = 5), TAN, total adenine nucleotides.