Table 5.

Comparison of day 0 vs. day 28 concentrations of urinary biomarkers of interest, for post-menopausal women consuming the treatment or a placebo.

Biomarker		Post-menopausal women n = 30
ng/mg creatinine		Treatment n = 17			Placebo n = 13
		Day 0	Day 28	P-value	Day 0	Day 28	P-value
2-OHE	Mean	9.22	17.37	0.035	10.29	11.9	0.656
	SD1	9.67	21.27		11.99	11.4
16α-OHE	Mean	2.70	3.92	0.057	4.30	3.79	0.556
	SD	2.23	2.63		3.43	1.81
2:16α-OHE ratio	Mean	4.54	5.40	0.387	3.20	4.13	0.570
	SD	4.81	4.77		4.14	4.87

¹Abbreviation: SD, standard deviation.