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Representative bioluminescence images of mice with luciferase-positive ST88-14 orthotopic xenografts (A), together with tumor region of interest data (mean ± standard error) over time for all mice (B), and tumor weights at termination (C). The tamoxifen pellet was implanted after imaging on Day 0. For Fig. 6B, the region of interest data for each mouse were normalized to its individual bioluminescence signal on Day 0 (×100%), prior to initiation of treatment.
