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Cardiac structural features of TK+/+ and TK−/− mice. (A) Two-dimensional echocardiography parameters determined in TK+/+ (n = 25) and TK−/− (n = 20) mice. (B) Histomorphometric cardiac dimensions measured on perfusion-fixed hearts isolated from the same animals at termination. The mean body weight was identical between TK+/+ and TK−/− mice (25.65 ± 0.52 versus 25.63 ± 0.44 g). Values (means ± SEM) have been compared by ANOVA.
