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. Author manuscript; available in PMC: 2012 Jan 1.
Published in final edited form as: Exp Neurol. 2010 Oct 13;227(1):104–109. doi: 10.1016/j.expneurol.2010.09.019

Figure 2. Time course of SR wind-up and habituation at various stretch intervals.

Figure 2

All values are normalized to the first stretch and group means are shown for peak plantarflexion torque at 49 days post Tx. Similar results were noted for gastrocnemius EMG. A) Regardless of stretch interval, Tx only animals (n=7) showed marked SR wind-up with a peak response occurring during stretch 2, 3, 4 for stretch intervals of 1 sec, 0.4 sec and 0.25 sec, respectively. Habituation of the response occurred rapidly with no evidence of SR wind-up by 2 sec. B) Modafinil treated animals (n=8) showed a slight increase in torque but values were not significantly increased compared to the first stretch. C) Exercise animals (n=8) failed to show evidence of SR wind-up at any stretch interval.