Table 3.
Evaluation of RNAi screens as a test set
Datatype_kernel | Signal-to-noise ratio |
---|---|
micro_linear | 1.44 |
micro_poly | 1.00 |
micro_RBF | 3.91 |
chip_binary_linear | 1.36 |
chip_binary_poly | 1.84 |
chip_binary_RBF | 1.88 |
chip_contin_linear | 1.57 |
chip_contin_poly | 1.86 |
chip_contin_RBF | 1.91 |
weight_binary_linear | 1.80 |
weight_binary_poly | 1.96 |
weight_binary_RBF | 3.82 |
weight_contin_linear | 1.84 |
weight_contin_poly | 1.65 |
weight_contin_RBF | 2.35 |
simple_binary_linear | 1.80 |
simple_binary_poly | 3.43 |
simple_binary_RBF | 3.80 |
simple_contin_linear | 1.84 |
simple_contin_poly | 1.38 |
simple_contin_RBF | 3.21 |
Ranked methods based on signal-to-noise ratio performance of predicting the percentage of genes as positive from the positive test set (self-renewal screen) and as positive from the negative test set (insulin-pathway screen).