Table 1.
Characteristics of healthy controls and CF patients, divided in subgroups according to P. aeruginosa infection status
| CF never/free/intermittent P. aeruginosa | CF chronic P. aeruginosa | control subjects | |
|---|---|---|---|
| Nr. of subjects | 17 | 21 | 11 |
| Age (mean ± SD) in years | 26.6 ± 8.0 | 25.1 ± 4.3 | 27.5 ± 10.9 |
| Gender (F/M) | 11/6 | 9/12 | 10/1 |
| BMI (mean ± SD) in kg/m2 | 21.6 ± 3.0 | 20.2 ± 2.5 | NA |
| Genotype (# of pts dF508del homozygous) | 2 | 16* | NA |
| Exocrine pancreas insufficiency (%) | 64.7 | 100** | NA |
| Current FEV1 (% predicted) (mean ± SD) | 72.8 ± 17 | 61.9 ± 17.4 | Normal values |
| Mean FEV1 previous year (% predicted) (mean ± SD) |
73.8 ± 16.6 | 65.1 ± 16.3 | NA |
SD: standard deviation, F: female, M: male, NA: not available, pts: patients.
*: p < 0.0001 (Chi-square test), **: p = 0.003 (Chi-square test).