Table 1.
Clinical characteristics of the child patients for this study
| Con-C | Early stage of BA | OPD | Late stage of BA | CC | |||
|---|---|---|---|---|---|---|---|
| Plasma | Plasma | Liver | Plasma | Plasma | Liver | Plasma & Liver | |
| Sample No | 7 | 41 | 9 | 25 | 49 | 9 | 9 |
| Age (months) | 18 ± 24 | 2.4 ± 1.2 | 2 ± 1 | 24 ± 16 | 15 ± 10 | 15 ± 6 | 22 ± 14 |
| Sex (M/F) | 4/3 | 23/16 | 4/5 | 7/18 | 19/21 | 4/5 | 2/7 |
| AST (U/l) | ND | 200 ± 175† | 181 ± 130 | ND | 276 ± 241 | 246 ± 114 | 298 ± 228 |
| T. Bil (mg/dl) | ND | 9.0 ± 2.9† | 9.4 ± 3.0 | ND | 16 ± 1.0 | 18 ± 10 | 6.5 ± 6.0† |
| D. Bil (mg/dl) | ND | 6.3 ± 2.0† | 7.0 ± 2.3† | ND | 12 ± 7.5 | 13 ± 7.2 | 5.6 ± 4.0† |
| sCD14 (μg/ml) | 4.0 ± 0.8 | 4.7 ± 1.7† | 47 ± 14 | 4.2 ± 1.4† | 2.7 ± 1.5*‡ | 49 ± 12 | 4.0 ± 2.0† |
| Endotoxin (EU/ml) | 2.0 ± 1.0 | 6.2 ± 5.0*‡ | 17 ± 4.0 | 2.2 ± 5.0† | 6.7 ± 5.0*‡ | 16 ± 7.0 | 6.5 ± 4.0*‡ |
Con-C, control-children; Early stage of BA, Kasai's procedure for biliary atresia; OPD, Jaundice-free post-Kasai BA patients followed at the outpatient department; Late stage of BA, liver transplantation for biliary atresia; CC, choledochal cyst; AST, alanine aminotransferase; D. Bil, direct bilirubin; T. Bil, total bilirubin; ND, non detection; sCD14, souble CD14; y, years. Value are expressed as the mean ± SD. *P < 0.05 vs control; †P < 0.05 vs late stage of BA; ‡P < 0.05 vs OPD.