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. 2001 Feb 20;98(5):2646–2651. doi: 10.1073/pnas.041622398

Figure 1.

Figure 1

View of gene cluster I and control gene expression levels for 48 blood samples. Healthy volunteers included 15 women with no history of breast disease; patients included 26 women with a variety of stages of breast cancer. Gene expression levels are color-coded according to key. Blood samples N0a, N0b, and N0c were drawn from the same individual at successive time points, as were samples N2a, N2b, N2c, N4a, and N4b. N2c(1) and N2c(2) represent two different experiments performed with the same sample of N2c RNA, as do N4a(1) and N4a(2). Cancer patients are ordered by stage of disease at the time of blood collection. Patients who had received any chemotherapy treatments before blood collection are indicated. (Middle) Five “housekeeping” genes as nondifferential controls. (Lower) Four genes commonly used as breast tumor markers. Full cluster diagram with all gene identities is available (see Fig. 5, which is published as supplemental data on the PNAS web site).