Figure 4.

Maximum likelihood tree of P. infestans TKL proteins and selected human TKLs. Leaves with P. infestans proteins are unlabeled, while human proteins start with the prefix Hs. In the upper corners, subtrees are shown to help illustrate relationships between the P. infestans proteins and RAF kinases (upper right) or between the two putative TKs and human STKR and RIPK (upper left); numbers at nodes are aLRT confidence numbers from PhyML. Human gene names are based on the nomenclature at http://kinase.com. Subfamily assignments of the P. infestans proteins in the tree are in Additional File 1 Table S1.